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A model of blood-ammonia homeostasis based on a quantitative analysis of nitrogen metabolism in the multiple organs involved in the production, catabolism, and excretion of ammonia in humans
Increased blood ammonia (NH(3)) is an important causative factor in hepatic encephalopathy, and clinical treatment of hepatic encephalopathy is focused on lowering NH(3). Ammonia is a central element in intraorgan nitrogen (N) transport, and modeling the factors that determine blood-NH(3) concentrat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973424/ https://www.ncbi.nlm.nih.gov/pubmed/29872332 http://dx.doi.org/10.2147/CEG.S160921 |