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The role of HIF-1α in chemo-/radioresistant tumors

Chemo-/radioresistance is a major obstacle in clinical oncology. The precise failure mechanisms of chemo-/radioresistance are multifactorial failures. It is now widely accepted that a tumor hypoxia microenvironment contributes significantly to chemo-/radioresistance. Hypoxia is the most common and o...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Jiang, Lixia, Zhong, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973460/
https://www.ncbi.nlm.nih.gov/pubmed/29872312
http://dx.doi.org/10.2147/OTT.S158206