Overexpression of Pyruvate Kinase Type M2 (PKM2) Promotes Ovarian Cancer Cell Growth and Survival Via Regulation of Cell Cycle Progression Related with Upregulated CCND1 and Downregulated CDKN1A Expression

BACKGROUND: Many findings have shown that pyruvate kinase type M2 (PKM2) plays crucial roles in regulating the occurrence and development of various human cancers; however, its roles in ovarian cancer oncogenesis remain to be determined. MATERIAL/METHODS: The expression intensity of PKM2 in ovarian...

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Detalles Bibliográficos
Autores principales: Zheng, Bin, Liu, Fangfang, Zeng, Li, Geng, Li, Ouyang, Xiaojuan, Wang, Kai, Huang, Qiaojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973491/
https://www.ncbi.nlm.nih.gov/pubmed/29752805
http://dx.doi.org/10.12659/MSM.907490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973491/
https://www.ncbi.nlm.nih.gov/pubmed/29752805
http://dx.doi.org/10.12659/MSM.907490

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