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Vaccine antigens modulate the innate response of monocytes to Al(OH)(3)

Aluminum-based adjuvants have widely been used in human vaccines since 1926. In the absence of antigens, aluminum-based adjuvants can initiate the inflammatory preparedness of innate cells, yet the impact of antigens on this response has not been investigated so far. In this study, we address the mo...

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Detalles Bibliográficos
Autores principales: Kooijman, Sietske, Brummelman, Jolanda, van Els, Cécile A. C. M., Marino, Fabio, Heck, Albert J. R., van Riet, Elly, Metz, Bernard, Kersten, Gideon F. A., Pennings, Jeroen L. A., Meiring, Hugo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973561/
https://www.ncbi.nlm.nih.gov/pubmed/29813132
http://dx.doi.org/10.1371/journal.pone.0197885