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Prefronto-cortical dopamine D1 receptor sensitivity can critically influence working memory maintenance during delayed response tasks

The dopamine (DA) hypothesis of cognitive deficits suggests that too low or too high extracellular DA concentration in the prefrontal cortex (PFC) can severely impair the working memory (WM) maintenance during delay period. Thus, there exists only an optimal range of DA where the sustained-firing ac...

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Detalles Bibliográficos
Autores principales: Reneaux, Melissa, Gupta, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973564/
https://www.ncbi.nlm.nih.gov/pubmed/29813109
http://dx.doi.org/10.1371/journal.pone.0198136