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Prefronto-cortical dopamine D1 receptor sensitivity can critically influence working memory maintenance during delayed response tasks
The dopamine (DA) hypothesis of cognitive deficits suggests that too low or too high extracellular DA concentration in the prefrontal cortex (PFC) can severely impair the working memory (WM) maintenance during delay period. Thus, there exists only an optimal range of DA where the sustained-firing ac...
Autores principales: | Reneaux, Melissa, Gupta, Rahul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973564/ https://www.ncbi.nlm.nih.gov/pubmed/29813109 http://dx.doi.org/10.1371/journal.pone.0198136 |
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