Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts

A xenobank of patient-derived (PDX) ovarian tumor samples has been established consisting of tumors with different sensitivity to cisplatin (DDP), from very responsive to resistant. As the DNA repair pathway is an important driver in tumor response to DDP, we analyzed the mRNA expression of 20 genes...

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Detalles Bibliográficos
Autores principales: Guffanti, Federica, Fratelli, Maddalena, Ganzinelli, Monica, Bolis, Marco, Ricci, Francesca, Bizzaro, Francesca, Chilà, Rosaria, Sina, Federica Paola, Fruscio, Robert, Lupia, Michela, Cavallaro, Ugo, Cappelletti, Maria Rosa, Generali, Daniele, Giavazzi, Raffaella, Damia, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973859/
https://www.ncbi.nlm.nih.gov/pubmed/29872499
http://dx.doi.org/10.18632/oncotarget.25185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973859/
https://www.ncbi.nlm.nih.gov/pubmed/29872499
http://dx.doi.org/10.18632/oncotarget.25185

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