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Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts
A xenobank of patient-derived (PDX) ovarian tumor samples has been established consisting of tumors with different sensitivity to cisplatin (DDP), from very responsive to resistant. As the DNA repair pathway is an important driver in tumor response to DDP, we analyzed the mRNA expression of 20 genes...
Autores principales: | Guffanti, Federica, Fratelli, Maddalena, Ganzinelli, Monica, Bolis, Marco, Ricci, Francesca, Bizzaro, Francesca, Chilà, Rosaria, Sina, Federica Paola, Fruscio, Robert, Lupia, Michela, Cavallaro, Ugo, Cappelletti, Maria Rosa, Generali, Daniele, Giavazzi, Raffaella, Damia, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973859/ https://www.ncbi.nlm.nih.gov/pubmed/29872499 http://dx.doi.org/10.18632/oncotarget.25185 |
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