CH2 Domain of Mouse IgG3 Governs Antibody Oligomerization, Increases Functional Affinity to Multivalent Antigens and Enhances Hemagglutination

Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates erythrocytes. IgG3 also triggers the complement cascade....

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Detalles Bibliográficos
Autores principales: Klaus, Tomasz, Bereta, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974032/
https://www.ncbi.nlm.nih.gov/pubmed/29875771
http://dx.doi.org/10.3389/fimmu.2018.01096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974032/
https://www.ncbi.nlm.nih.gov/pubmed/29875771
http://dx.doi.org/10.3389/fimmu.2018.01096

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