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Vitamin D Genomics: From In Vitro to In Vivo
The vitamin D(3) metabolite 1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] is the exclusive high-affinity ligand of the vitamin D receptor (VDR), a transcription factor with direct effects on gene expression. Transcriptome- and epigenome-wide data obtained in THP-1 human monocytes are the basis of th...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974042/ https://www.ncbi.nlm.nih.gov/pubmed/29875733 http://dx.doi.org/10.3389/fendo.2018.00250 |