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Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice
Neuregulin 1 (NRG1) is required for development of the central and peripheral nervous system and regulates neurotransmission in the adult. NRG1 and the gene encoding its receptor, ERBB4, are risk genes for schizophrenia, although how alterations in these genes disrupt their function has not been ful...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974084/ https://www.ncbi.nlm.nih.gov/pubmed/29844389 http://dx.doi.org/10.1038/s41598-018-26492-4 |