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Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice

Neuregulin 1 (NRG1) is required for development of the central and peripheral nervous system and regulates neurotransmission in the adult. NRG1 and the gene encoding its receptor, ERBB4, are risk genes for schizophrenia, although how alterations in these genes disrupt their function has not been ful...

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Detalles Bibliográficos
Autores principales: Dominguez, Sara L., Hegde, Ganapati V., Hanson, Jesse E., Xiang, Hong, Mandikian, Danielle, Boswell, C. Andrew, Chiu, Cecilia, Wu, Yan, Tsai, Siao Ping, Fleck, Daniel, Weber, Martin, Ngu, Hai, Scearce-Levie, Kimberly, Jackson, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974084/
https://www.ncbi.nlm.nih.gov/pubmed/29844389
http://dx.doi.org/10.1038/s41598-018-26492-4