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Nanopore sequencing of drug-resistance-associated genes in malaria parasites, Plasmodium falciparum

Here, we report the application of a portable sequencer, MinION, for genotyping the malaria parasite Plasmodium falciparum. In the present study, an amplicon mixture of nine representative genes causing resistance to anti-malaria drugs is diagnosed. First, we developed the procedure for four laborat...

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Detalles Bibliográficos
Autores principales: Runtuwene, Lucky R., Tuda, Josef S. B., Mongan, Arthur E., Makalowski, Wojciech, Frith, Martin C., Imwong, Mallika, Srisutham, Suttipat, Nguyen Thi, Lan Anh, Tuan, Nghia Nguyen, Eshita, Yuki, Maeda, Ryuichiro, Yamagishi, Junya, Suzuki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974085/
https://www.ncbi.nlm.nih.gov/pubmed/29844487
http://dx.doi.org/10.1038/s41598-018-26334-3