Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR

P53-binding protein 1 (53BP1) regulates the double-strand break (DSB) repair pathway choice. A recently identified 53BP1-binding protein Tudor-interacting repair regulator (TIRR) modulates the access of 53BP1 to DSBs by masking the H4K20me2 binding surface on 53BP1, but the underlying mechanism rema...

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Detalles Bibliográficos
Autores principales: Dai, Yaxin, Zhang, Aili, Shan, Shan, Gong, Zihua, Zhou, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974088/
https://www.ncbi.nlm.nih.gov/pubmed/29844495
http://dx.doi.org/10.1038/s41467-018-04557-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974088/
https://www.ncbi.nlm.nih.gov/pubmed/29844495
http://dx.doi.org/10.1038/s41467-018-04557-2

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