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The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4(+) T Cells During Viral Infection
Follicular helper CD4(+) T (T(FH)) cells are critical for optimal B-cell-mediated humoral immunity by initiating, fueling, and sustaining germinal center reactions. The differentiation of T(FH) cells relies on multiple intrinsic and extrinsic factors; however, the details by which these factors are...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974104/ https://www.ncbi.nlm.nih.gov/pubmed/29875775 http://dx.doi.org/10.3389/fimmu.2018.01127 |