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Male germ cells support long-term propagation of Zika virus

Evidence of male-to-female sexual transmission of Zika virus (ZIKV) and viral RNA in semen and sperm months after infection supports a potential role for testicular cells in ZIKV propagation. Here, we demonstrate that germ cells (GCs) are most susceptible to ZIKV. We found that only GCs infected by...

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Detalles Bibliográficos
Autores principales: Robinson, Christopher L., Chong, Angie C. N., Ashbrook, Alison W., Jeng, Ginnie, Jin, Julia, Chen, Haiqi, Tang, Elizabeth I., Martin, Laura A., Kim, Rosa S., Kenyon, Reyn M., Do, Eileen, Luna, Joseph M., Saeed, Mohsan, Zeltser, Lori, Ralph, Harold, Dudley, Vanessa L., Goldstein, Marc, Rice, Charles M., Cheng, C. Yan, Seandel, Marco, Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974187/
https://www.ncbi.nlm.nih.gov/pubmed/29844387
http://dx.doi.org/10.1038/s41467-018-04444-w