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Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration

In animal regeneration, control of position-dependent cell proliferation is crucial for the complete restoration of patterned appendages in terms of both, shape and size. However, detailed mechanisms of this process are largely unknown. In this study, we identified leucine/glutamine and v-ATPase/lys...

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Detalles Bibliográficos
Autores principales: Takayama, Kazuya, Muto, Akihiko, Kikuchi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974189/
https://www.ncbi.nlm.nih.gov/pubmed/29844341
http://dx.doi.org/10.1038/s41598-018-26664-2