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Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration
In animal regeneration, control of position-dependent cell proliferation is crucial for the complete restoration of patterned appendages in terms of both, shape and size. However, detailed mechanisms of this process are largely unknown. In this study, we identified leucine/glutamine and v-ATPase/lys...
Autores principales: | Takayama, Kazuya, Muto, Akihiko, Kikuchi, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974189/ https://www.ncbi.nlm.nih.gov/pubmed/29844341 http://dx.doi.org/10.1038/s41598-018-26664-2 |
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