Rational Design and Evaluation of an Artificial Escherichia coli K1 Protein Vaccine Candidate Based on the Structure of OmpA

Escherichia coli (E. coli) K1 causes meningitis and remains an unsolved problem in neonates, despite the application of antibiotics and supportive care. The cross-reactivity of bacterial capsular polysaccharides with human antigens hinders their application as vaccine candidates. Thus, protein antig...

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Detalles Bibliográficos
Autores principales: Gu, Hao, Liao, Yaling, Zhang, Jin, Wang, Ying, Liu, Zhiyong, Cheng, Ping, Wang, Xingyong, Zou, Quanming, Gu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974202/
https://www.ncbi.nlm.nih.gov/pubmed/29876324
http://dx.doi.org/10.3389/fcimb.2018.00172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974202/
https://www.ncbi.nlm.nih.gov/pubmed/29876324
http://dx.doi.org/10.3389/fcimb.2018.00172

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