The Anti-inflammatory Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Stimulated Endothelial Cells via Activation of GPR41/43 and Inhibition of HDACs

Background and Aim: Previously, we found that short chain fatty acids (SCFA) inhibit LPS or TNFα-induced endothelial inflammatory responses and excessive vascular cell adhesion molecule-1 (VCAM-1) expression, two important steps in the development of atherosclerosis. However, the mechanisms involved...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Meng, van Esch, Betty C. A. M., Henricks, Paul A. J., Folkerts, Gert, Garssen, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974203/
https://www.ncbi.nlm.nih.gov/pubmed/29875665
http://dx.doi.org/10.3389/fphar.2018.00533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974203/
https://www.ncbi.nlm.nih.gov/pubmed/29875665
http://dx.doi.org/10.3389/fphar.2018.00533

Ejemplares similares