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Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage

Hearing loss is the most common sensory disorder in humans, and a significant number of cases is due to the ototoxicity of drugs such as cisplatin that cause hair cell (HC) damage. Thus, there is great interest in finding agents and mechanisms that protect HCs from ototoxic drug damage. It has been...

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Detalles Bibliográficos
Autores principales: Li, He, Song, Yongdong, He, Zuhong, Chen, Xiaoyun, Wu, Xianmin, Li, Xiaofei, Bai, Xiaohui, Liu, Wenwen, Li, Boqin, Wang, Shanshan, Han, Yuechen, Xu, Lei, Zhang, Daogong, Li, Jianfeng, Chai, Renjie, Wang, Haibo, Fan, Zhaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974247/
https://www.ncbi.nlm.nih.gov/pubmed/29875633
http://dx.doi.org/10.3389/fncel.2018.00139