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Broad distribution spectrum from Gaussian to power law appears in stochastic variations in RNA-seq data

Gene expression levels exhibit stochastic variations among genetically identical organisms under the same environmental conditions. In many recent transcriptome analyses based on RNA sequencing (RNA-seq), variations in gene expression levels among replicates were assumed to follow a negative binomia...

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Detalles Bibliográficos
Autores principales: Awazu, Akinori, Tanabe, Takahiro, Kamitani, Mari, Tezuka, Ayumi, Nagano, Atsushi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974282/
https://www.ncbi.nlm.nih.gov/pubmed/29844539
http://dx.doi.org/10.1038/s41598-018-26735-4