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Homodimerisation-independent cleavage of dsRNA by a pestiviral nicking endoribonuclease

The glycoprotein E(rns) plays a central role in the biology of the pestivirus bovine viral diarrhea virus (BVDV). This soluble endonuclease mediates the escape from an interferon (IFN) response in the infected fetus, thereby permitting the establishment of persistent infection. Viral single-stranded...

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Detalles Bibliográficos
Autores principales: Lussi, Carmela, Sauter, Kay-Sara, Schweizer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974291/
https://www.ncbi.nlm.nih.gov/pubmed/29844335
http://dx.doi.org/10.1038/s41598-018-26557-4