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A machine learning approach to predict metabolic pathway dynamics from time-series multiomics data

New synthetic biology capabilities hold the promise of dramatically improving our ability to engineer biological systems. However, a fundamental hurdle in realizing this potential is our inability to accurately predict biological behavior after modifying the corresponding genotype. Kinetic models ha...

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Detalles Bibliográficos
Autores principales: Costello, Zak, Martin, Hector Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974308/
https://www.ncbi.nlm.nih.gov/pubmed/29872542
http://dx.doi.org/10.1038/s41540-018-0054-3