miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP

Although evidence has emerged to suggest that YAP overexpression is a crucial factor for tumor progression and resistance to targeted drugs in multiple cancers, the miRNA-mediated YAP regulation is still unclear. Here we show that the novel miR-550a-3-5p acts as a tumor suppressor and reverses BRAF...

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Detalles Bibliográficos
Autores principales: Choe, Min Ho, Yoon, Yina, Kim, Joon, Hwang, Sang-Gu, Han, Young-Hoon, Kim, Jae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974323/
https://www.ncbi.nlm.nih.gov/pubmed/29844307
http://dx.doi.org/10.1038/s41419-018-0698-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974323/
https://www.ncbi.nlm.nih.gov/pubmed/29844307
http://dx.doi.org/10.1038/s41419-018-0698-3

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