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SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function

Rhabdomyosarcoma (RMS) is a mesenchymal tumor of soft tissue in children that originates from a myogenic differentiation defect. Expression of SNAIL transcription factor is elevated in the alveolar subtype of RMS (ARMS), characterized by a low myogenic differentiation status and high aggressiveness....

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Detalles Bibliográficos
Autores principales: Skrzypek, Klaudia, Kusienicka, Anna, Trzyna, Elzbieta, Szewczyk, Barbara, Ulman, Aleksandra, Konieczny, Pawel, Adamus, Tomasz, Badyra, Bogna, Kortylewski, Marcin, Majka, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974324/
https://www.ncbi.nlm.nih.gov/pubmed/29844345
http://dx.doi.org/10.1038/s41419-018-0693-8