Linking drug target and pathway activation for effective therapy using multi-task learning

Despite the abundance of large-scale molecular and drug-response data, the insights gained about the mechanisms underlying treatment efficacy in cancer has been in general limited. Machine learning algorithms applied to those datasets most often are used to provide predictions without interpretation...

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Detalles Bibliográficos
Autores principales: Yang, Mi, Simm, Jaak, Lam, Chi Chung, Zakeri, Pooya, van Westen, Gerard J. P., Moreau, Yves, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974390/
https://www.ncbi.nlm.nih.gov/pubmed/29844324
http://dx.doi.org/10.1038/s41598-018-25947-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974390/
https://www.ncbi.nlm.nih.gov/pubmed/29844324
http://dx.doi.org/10.1038/s41598-018-25947-y

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