The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model

Alzheimer’s disease (AD) is a dreadful neurodegenerative disease that leads to severe impairment of cognitive function, leading to a drastic decline in the quality of life. The primary pathological features of AD include senile plaques (SPs) and intracellular neurofibrillary tangles (NFTs), comprisi...

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Detalles Bibliográficos
Autores principales: Fan, Sheng-Jun, Huang, Fang-I, Liou, Jing-Ping, Yang, Chia-Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974403/
https://www.ncbi.nlm.nih.gov/pubmed/29844403
http://dx.doi.org/10.1038/s41419-018-0688-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974403/
https://www.ncbi.nlm.nih.gov/pubmed/29844403
http://dx.doi.org/10.1038/s41419-018-0688-5

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