Induction of ganglioside synthesis in Drosophila brain accelerates assembly of amyloid β protein

The assembly and deposition of amyloid β protein (Aβ) is a fundamental event during the early stages of Alzheimer’s disease (AD) and cerebral amyloid angiopathy. A growing body of evidence indicates that gangliosides form a pathological platform for the generation of ganglioside-bound Aβ, which faci...

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Detalles Bibliográficos
Autores principales: Yamasaki, Yasutoyo, Tsuda, Leo, Suzuki, Akemi, Yanagisawa, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974419/
https://www.ncbi.nlm.nih.gov/pubmed/29844375
http://dx.doi.org/10.1038/s41598-018-26294-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974419/
https://www.ncbi.nlm.nih.gov/pubmed/29844375
http://dx.doi.org/10.1038/s41598-018-26294-8

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