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Induction of ganglioside synthesis in Drosophila brain accelerates assembly of amyloid β protein
The assembly and deposition of amyloid β protein (Aβ) is a fundamental event during the early stages of Alzheimer’s disease (AD) and cerebral amyloid angiopathy. A growing body of evidence indicates that gangliosides form a pathological platform for the generation of ganglioside-bound Aβ, which faci...
Autores principales: | Yamasaki, Yasutoyo, Tsuda, Leo, Suzuki, Akemi, Yanagisawa, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974419/ https://www.ncbi.nlm.nih.gov/pubmed/29844375 http://dx.doi.org/10.1038/s41598-018-26294-8 |
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