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Isospecific adenine DNA methyltransferases show distinct preferences towards DNA substrates

Here, we report results on systematic analysis of DNA substrate preferences of three N6-adenine β-class DNA methyltransferases that are part of the type II restriction-modification systems. The studied enzymes were: M.EcoVIII, M.HindIII and M.LlaCI, which although found in phylogenetically distant b...

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Detalles Bibliográficos
Autores principales: Wons, Ewa, Mruk, Iwona, Kaczorowski, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974420/
https://www.ncbi.nlm.nih.gov/pubmed/29844340
http://dx.doi.org/10.1038/s41598-018-26434-0