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An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts
Lasso peptides are ribosomally synthesized and post-translationally modified peptides produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted genome scanning revealed a wide diversity of lasso peptides encoded in actinobacterial genomes, but cloning and heterologou...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974421/ https://www.ncbi.nlm.nih.gov/pubmed/29844351 http://dx.doi.org/10.1038/s41598-018-26620-0 |