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An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts

Lasso peptides are ribosomally synthesized and post-translationally modified peptides produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted genome scanning revealed a wide diversity of lasso peptides encoded in actinobacterial genomes, but cloning and heterologou...

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Detalles Bibliográficos
Autores principales: Mevaere, Jimmy, Goulard, Christophe, Schneider, Olha, Sekurova, Olga N., Ma, Haiyan, Zirah, Séverine, Afonso, Carlos, Rebuffat, Sylvie, Zotchev, Sergey B., Li, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974421/
https://www.ncbi.nlm.nih.gov/pubmed/29844351
http://dx.doi.org/10.1038/s41598-018-26620-0