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Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates

During exposure to ionizing radiation, sub-lethal damage repair (SLDR) competes with DNA damage induction in cultured cells. By virtue of SLDR, cell survival increases with decrease of dose-rate, so-called dose-rate effects (DREs). Here, we focused on a wide dose-rate range and investigated the chan...

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Detalles Bibliográficos
Autores principales: Matsuya, Yusuke, McMahon, Stephen J., Tsutsumi, Kaori, Sasaki, Kohei, Okuyama, Go, Yoshii, Yuji, Mori, Ryosuke, Oikawa, Joma, Prise, Kevin M., Date, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974424/
https://www.ncbi.nlm.nih.gov/pubmed/29844494
http://dx.doi.org/10.1038/s41598-018-26556-5