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The Phosphatase PTPL1 Is Required for PTEN-Mediated Regulation of Apical Membrane Size
PTEN is a tumor suppressor that is frequently lost in epithelial malignancies. A part of the tumor-suppressive properties of PTEN is attributed to its function in cell polarization and consequently its role in maintaining epithelial tissue integrity. However, surprisingly little is known about the f...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974425/ https://www.ncbi.nlm.nih.gov/pubmed/29581186 http://dx.doi.org/10.1128/MCB.00102-18 |