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Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries. An in vitro NAFLD model would permit mechanistic studies and enable high-throughput therapeutic screening. While hepatic cancer-derived cell lines are a convenient, renewable resource, their g...

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Detalles Bibliográficos
Autores principales: Lyall, Marcus J., Cartier, Jessy, Thomson, John P., Cameron, Kate, Meseguer-Ripolles, Jose, O'Duibhir, Eoghan, Szkolnicka, Dagmara, Villarin, Baltasar Lucendo, Wang, Yu, Blanco, Giovanny Rodriguez, Dunn, Warwick B., Meehan, Richard R., Hay, David C., Drake, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974453/
https://www.ncbi.nlm.nih.gov/pubmed/29786565
http://dx.doi.org/10.1098/rstb.2017.0362