Cargando…

Production of transgenic pigs using a pGFAP-CreER(T2)/EGFP(LoxP) inducible system for central nervous system disease models

Transgenic (TG) pigs are important in biomedical research and are used in disease modeling, pharmaceutical toxicity testing, and regenerative medicine. In this study, we constructed two vector systems by using the promoter of the pig glial fibrillary acidic protein (pGFAP) gene, which is an astrocyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Seon-Ung, Eun, Kiyoung, Yoon, Junchul David, Kim, Hyunggee, Hyun, Sang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974525/
https://www.ncbi.nlm.nih.gov/pubmed/29284207
http://dx.doi.org/10.4142/jvs.2018.19.3.434