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HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons

Emerging evidence showed that hyperpolarization-activated cation channels (HCN) participate in the development of inflammatory and neuropathic pain. However, the role of HCN2 in oxaliplatin-induced neuropathic pain remains unknown. Here, we found that HCN2 expression was upregulated in a rat model o...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyu, Zhang, Lidong, Jin, Li, Tan, Yuanhui, Li, Weiyan, Tang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974562/
https://www.ncbi.nlm.nih.gov/pubmed/29806529
http://dx.doi.org/10.1177/1744806918778490