Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells

Oxymatrine (OMT) often used in treatment for chronic hepatitis B virus infection in clinic. However, OMT–induced liver injury has been reported. In this study, we aim to investigate the possible mechanism of OMT-induced hepatotoxicity in human normal liver cells (L02). Exposed cells to OMT, the cell...

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Detalles Bibliográficos
Autores principales: Gu, Li-li, Shen, Zhe-lun, Li, Yang-Lei, Bao, Yi-Qi, Lu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974617/
https://www.ncbi.nlm.nih.gov/pubmed/29754474
http://dx.doi.org/10.14348/molcells.2018.2180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974617/
https://www.ncbi.nlm.nih.gov/pubmed/29754474
http://dx.doi.org/10.14348/molcells.2018.2180

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