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Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression

Recently, we have reported that animals with telomerase reverse transcriptase (TERT) overexpression exhibit reduced social interaction, decreased preference for novel social interaction and poor nest-building behaviors symptoms that mirror those observed in human autism spectrum disorders (ASD). Ove...

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Detalles Bibliográficos
Autores principales: Rhee, Jeehae, Park, Kwanghoon, Kim, Ki Chan, Shin, Chan Young, Chung, ChiHye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974625/
https://www.ncbi.nlm.nih.gov/pubmed/29696935
http://dx.doi.org/10.14348/molcells.2018.0145