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Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria

[Image: see text] Two new bracelet cyclotides from roots of Pombalia calceolaria with potential anticancer activity have been characterized in this work. The cyclotides Poca A and B (1 and 2) and the previously known CyO4 (3) were de novo sequenced by MALDI-TOF/TOF mass spectrometry (MS). The MS(2)...

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Detalles Bibliográficos
Autores principales: Pinto, Meri Emili F., Najas, Jhenny Z. G., Magalhães, Luma G., Bobey, Antonio F., Mendonça, Jacqueline N., Lopes, Norberto P., Leme, Flávia M., Teixeira, Simone P., Trovó, Marcelo, Andricopulo, Adriano D., Koehbach, Johannes, Gruber, Christian W., Cilli, Eduardo Maffud, Bolzani, Vanderlan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974699/
https://www.ncbi.nlm.nih.gov/pubmed/29757646
http://dx.doi.org/10.1021/acs.jnatprod.7b00969