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NKp44-Derived Peptide Binds Proliferating Cell Nuclear Antigen and Mediates Tumor Cell Death

Proliferating cell nuclear antigen (PCNA) is considered as a hub protein and is a key regulator of DNA replication, repair, cell cycle control, and apoptosis. PCNA is overexpressed in many cancer types, and PCNA overexpression is correlated with cancer virulence. Membrane-associated PCNA is a ligand...

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Detalles Bibliográficos
Autores principales: Shemesh, Avishai, Kundu, Kiran, Peleg, Refael, Yossef, Rami, Kaplanov, Irena, Ghosh, Susmita, Khrapunsky, Yana, Gershoni-Yahalom, Orly, Rabinski, Tatiana, Cerwenka, Adelheid, Atlas, Roee, Porgador, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974751/
https://www.ncbi.nlm.nih.gov/pubmed/29875773
http://dx.doi.org/10.3389/fimmu.2018.01114