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DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair

Mutations in mitochondrial DNA (mtDNA) are associated with aging, and they can cause tissue degeneration and neuromuscular pathologies known as mitochondrial diseases. Because DNA polymerase γ (pol γ) is the enzyme responsible for replication and repair of mitochondrial DNA, the burden of faithful d...

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Detalles Bibliográficos
Autores principales: Copeland, William C., Longley, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974855/
https://www.ncbi.nlm.nih.gov/pubmed/12806118
http://dx.doi.org/10.1100/tsw.2003.09