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DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair
Mutations in mitochondrial DNA (mtDNA) are associated with aging, and they can cause tissue degeneration and neuromuscular pathologies known as mitochondrial diseases. Because DNA polymerase γ (pol γ) is the enzyme responsible for replication and repair of mitochondrial DNA, the burden of faithful d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974855/ https://www.ncbi.nlm.nih.gov/pubmed/12806118 http://dx.doi.org/10.1100/tsw.2003.09 |