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Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose

The objective of this study was to identify differences in disposition and esterase hydrolysis of ramipril between male and female volunteers. Plasma concentration and area under the concentration-time curve until the last measured concentration (AUCt) data of ramipril and its active metabolite rami...

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Detalles Bibliográficos
Autores principales: Vree, Tom B., Dammers, Erik, Ulc, Ivan, Horkovics-Kovats, Stefan, Ryska, Miroslav, Merkx, IJsbrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974869/
https://www.ncbi.nlm.nih.gov/pubmed/29887764
http://dx.doi.org/10.1100/tsw.2003.122