N‐methyl‐d‐aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines

ESSENTIALS: Intracellular calcium pathways regulate megakaryopoiesis but details are unclear. We examined effects of NMDAR‐mediated calcium influx on normal and leukemic cells in culture. NMDARs facilitated differentiation of normal but proliferation of leukemic megakaryocytes. NMDAR inhibitors indu...

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Detalles Bibliográficos
Autores principales: Kamal, Tania, Green, Taryn N., Hearn, James I., Josefsson, Emma C., Morel‐Kopp, Marie‐Christine, Ward, Christopher M., During, Matthew J., Kalev‐Zylinska, Maggie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles: Haemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974914/
https://www.ncbi.nlm.nih.gov/pubmed/30046713
http://dx.doi.org/10.1002/rth2.12068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974914/
https://www.ncbi.nlm.nih.gov/pubmed/30046713
http://dx.doi.org/10.1002/rth2.12068

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