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Effects of anti‐β2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity

ESSENTIALS: The antiphospholipid syndrome predisposes to thrombosis due to activation of endothelium and blood components. The role of anti‐β2GPI antibodies in VWF release and ADAMTS13 function is not well understood. Some anti‐β2GPI antibodies induce endothelial release of soluble VWF but not VWF s...

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Detalles Bibliográficos
Autores principales: Ng, Christopher J., McCrae, Keith R., Ashworth, Katrina, Sosa, Lucas J., Betapudi, Venkaiah, Manco‐Johnson, Marilyn J., Liu, Alice, Dong, Jing‐Fei, Chung, Dominic, White‐Adams, Tara C., López, José A., Di Paola, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974922/
https://www.ncbi.nlm.nih.gov/pubmed/30046742
http://dx.doi.org/10.1002/rth2.12090