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Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: A phase 1 clinical trial

INTRODUCTION: We conducted a phase 1 clinical trial in nine patients with mild-to-moderate Alzheimer's disease to evaluate the safety and dose-limiting toxicity of stereotactic brain injection of human umbilical cord blood–derived mesenchymal stem cells (hUCB-MSCs). METHODS: The low- (n = 3) an...

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Detalles Bibliográficos
Autores principales: Kim, Hee Jin, Seo, Sang Won, Chang, Jong Wook, Lee, Jung Il, Kim, Chi Hun, Chin, Juhee, Choi, Soo Jin, Kwon, Hunki, Yun, Hyuk Jin, Lee, Jong Min, Kim, Sung Tae, Choe, Yearn Seong, Lee, Kyung-Han, Na, Duk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975048/
https://www.ncbi.nlm.nih.gov/pubmed/29854930
http://dx.doi.org/10.1016/j.trci.2015.06.007