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A 24-week study to evaluate the effect of rilapladib on cognition and cerebrospinal fluid biomarkers of Alzheimer's disease
BACKGROUND: The lipoprotein-associated phospholipase A(2) inhibitor (Lp-PLA(2)), rilapladib (SB659032), is being evaluated as a potential treatment to slow the progression of Alzheimer's disease (AD). METHODS: One hundred twenty-four subjects with possible mild AD and with neuroimaging evidence...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975052/ https://www.ncbi.nlm.nih.gov/pubmed/29854933 http://dx.doi.org/10.1016/j.trci.2015.06.003 |