2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells

Peripheral leukocytes induce blood-brain barrier (BBB) dysfunction through the release of cytotoxic mediators. These include hypochlorous acid (HOCl) that is formed via the myeloperoxidase-H(2)O(2)-chloride system of activated phagocytes. HOCl targets the endogenous pool of ether phospholipids (plas...

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Detalles Bibliográficos
Autores principales: Bernhart, Eva, Kogelnik, Nora, Prasch, Jürgen, Gottschalk, Benjamin, Goeritzer, Madeleine, Depaoli, Maria Rosa, Reicher, Helga, Nusshold, Christoph, Plastira, Ioanna, Hammer, Astrid, Fauler, Günter, Malli, Roland, Graier, Wolfgang F., Malle, Ernst, Sattler, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975063/
https://www.ncbi.nlm.nih.gov/pubmed/29413957
http://dx.doi.org/10.1016/j.redox.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975063/
https://www.ncbi.nlm.nih.gov/pubmed/29413957
http://dx.doi.org/10.1016/j.redox.2018.01.003

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