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Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity
Damage to mitochondria and subsequent ROS leakage is a commonly accepted mechanism of nanoparticle toxicity. However, malfunction of mitochondria results in generation of superoxide anion radical (O(2)(•)-), which due to the relatively low chemical reactivity is rather unlikely to cause harmful effe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975067/ https://www.ncbi.nlm.nih.gov/pubmed/29351884 http://dx.doi.org/10.1016/j.redox.2018.01.006 |