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Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1

Disruption of endothelial monolayer integrity is the primary instigating factor for many cardiovascular diseases. High density lipoprotein (HDL) oxidized by heme enzyme myeloperoxidase (MPO) is dysfunctional in promoting endothelial repair. Apolipoprotein A-1 mimetic 4F with its pleiotropic benefits...

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Detalles Bibliográficos
Autores principales: He, Dan, Zhao, Mingming, Wu, Congying, Zhang, Wenjing, Niu, Chenguang, Yu, Baoqi, Jin, Jingru, Ji, Liang, Willard, Belinda, Mathew, Anna V., Chen, Y. Eugene, Pennathur, Subramaniam, Yin, Huiyong, He, Yuan, Pan, Bing, Zheng, Lemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975068/
https://www.ncbi.nlm.nih.gov/pubmed/29277016
http://dx.doi.org/10.1016/j.redox.2017.11.027